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Drug-related problem in children with chronic kidney disease

Norkasihan Ibrahim1, Ian Ck Wong, Susan Patey

  • 1Department of Practice and Policy, Centre for Paediatric Pharmacy Research (CPPR), University College London School of Pharmacy, British Medical Association/Tavistock House, Entrance A, 1st Floor Tavistock Square, London, WC1H 9JP, UK. nkasihanucl@gmail.com

Pediatric Nephrology (Berlin, Germany)
|March 28, 2012
PubMed

Insights

Drug-related problems (DRP) are common in children with chronic kidney disease (CKD). More research is needed to understand and manage these issues in pediatric CKD patients.

Area of Science:

  • Pediatric Nephrology
  • Clinical Pharmacy
  • Pharmacovigilance

Background:

  • Drug therapies for chronic kidney disease (CKD) are complex, posing a high risk of drug-related problems (DRP).
  • In adults with CKD, resolving DRP improves disease management, adherence, quality of life, and reduces healthcare costs.
  • Limited information exists regarding DRP in pediatric CKD populations.

Purpose of the Study:

  • To review published studies on drug-related problems (DRP) in children with chronic kidney disease (CKD).
  • To highlight the lack of epidemiological data on DRP in pediatric CKD.
  • To emphasize the need for further research in this area.

Main Methods:

  • Literature review of published studies.
  • Focus on studies concerning DRP in pediatric CKD patients.

Main Results:

  • A significant lack of published studies on the epidemiology of DRP in children with CKD was identified.
  • Existing literature on DRP in adult CKD populations demonstrates clear benefits from DRP identification and resolution.

Conclusions:

  • There is a critical need for research into the epidemiology and management of DRP in pediatric CKD.
  • Understanding and addressing DRP in children with CKD is essential for optimizing treatment outcomes and patient well-being.

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