Related Experiment Video
Updated: May 23, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Fever of unknown origin: large vessel vasculitis diagnosed by PET/CT
Dubravka Bosnić1, Marko Barešić, Ivan Padjen
1Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Kispaticeva 12, Zagreb, Croatia.
Positron emission tomography/computed tomography (PET/CT) aids in diagnosing fever of unknown origin (FUO). This case highlights PET/CT
Area of Science:
- Nuclear Medicine
- Radiology
- Rheumatology
Background:
- Fever of unknown origin (FUO) presents a diagnostic challenge.
- Giant cell arteritis (GCA) is a form of large vessel vasculitis.
- Early diagnosis and treatment are crucial for GCA management.
Observation:
- A 72-year-old female presented with a 4-month history of FUO, weight loss, and fatigue.
- Initial investigations revealed an acute phase response and microcytic anemia.
- Positron emission tomography/computed tomography (PET/CT) was performed to investigate suspected neoplastic proliferation.
Findings:
- PET/CT revealed extensive large vessel vasculitis involving the aorta and major arteries.
- Superficial temporal artery biopsy confirmed the diagnosis of giant cell arteritis (GCA).
- PET/CT successfully identified inflammation in large vessels not typically assessed by biopsy.
Implications:
- PET/CT is a valuable tool for evaluating FUO, particularly in suspected vasculitis.
- PET/CT can complement traditional diagnostic methods like temporal artery biopsy in GCA.
- This case underscores the utility of PET/CT in diagnosing GCA and other large vessel vasculitides.
More Related Videos
08:48Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Acute Pyelonephritis II: Diagnostic Studies and Management
Myocarditis II: Clinical Features and Diagnostic Tests
Imaging Studies for Cardiovascular System V: CT
Types of Fever
Here are the different types of fever:
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies