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[Studies on the antidiabetic effect of konjac glucomannan with different molecular chains on experimental diabetes
Chunmei Li1, Yuanyuan Wang, Wei He
1Department of Food Science and Technology, Huazhong Agriculture University, Wuhan 430070.
Abstract:
The antidiabetic effect of konjac glucomannan with different molecular chains on experimental diabetes mice was studied. The result showed that KGM- I, KGM-II, KGM-III and konjac flour can lower blood sugar of alloxan-induced hyperglycemic mice. When the dose was 1.5 g/kg, the decrease rates of blood sugar was 55.37%, 80.60%, 33.44% and 40.9%, respectively. It also showed that KGM-II (Po, 0.2 g/kg. d x 7d) can significantly intensify DTH induced by DNFB and improve phagocytosing function of peritoneal macrophage (PM phi) separetely.
