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Thromboprophylaxis for women undergoing caesarean section
C Kennedy1, V O'Dwyer, S O'Kelly
1UCD Centre for Human Reproduction, Coombe Women and Infant's University Hospital, Cork St, Dublin 8.
Irish Medical Journal
|March 30, 2012
Summary
This audit found that while all women received tinzaparin for caesarean section (CS) thromboprophylaxis, 94% received a suboptimal dose. This highlights a potential risk for venous thromboembolism despite prophylaxis measures.
Area of Science:
- Obstetrics and Gynecology
- Pharmacology
- Vascular Medicine
Background:
- Thromboprophylaxis is crucial for women undergoing caesarean section (CS) to prevent venous thromboembolism (VTE).
- Tinzaparin prophylaxis was implemented in the hospital in 1995.
- This study focuses on a specific cohort of women screened negative for diabetes mellitus.
Purpose of the Study:
- To audit the utilization and dosage of tinzaparin prophylaxis in women undergoing CS.
- To assess compliance with recommended tinzaparin dosages in this patient group.
- To identify potential risks for VTE despite prophylaxis.
Main Methods:
- A nested cohort study design was employed.
- Data collected included weight, BMI, and tinzaparin dosage administered.
- Audit of tinzaparin prophylaxis use in women who had a CS.
Main Results:
- Of 284 women, 68 (24%) underwent CS and received tinzaparin.
- 94% of these 68 women received a tinzaparin dose lower than recommended.
- Prophylaxis administration was complete, but dosage compliance was suboptimal.
Conclusions:
- Suboptimal dosing of tinzaparin in women undergoing CS may compromise VTE prevention.
- Further investigation into dosage adherence and VTE outcomes is warranted.
- Ensuring correct dosing is critical for effective thromboprophylaxis after CS.
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