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[Prevalence of hypercalciuria in postmenopausal women with osteoporosis]
Mauricio Carvalho1, Carolina Aguiar Moreira Kulak, Victória Zegbi Cochenski Borba
1Departamento de Clínica Médica e Serviço de Endocrinologia e Metabologia, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba, PR, Brasil. carvalho@mais.sul.com.br
Objective:
To determine the prevalence of hypercalciuria (HC) in postmenopausal women with osteoporosis and its relationship with clinical data and bone mineral metabolism.
Subjects And Methods:
Calciuria was measured in 24-hour urine samples of 127 women. BMD was measured in the lumbar spine and femur by dual-energy X-ray absorptiometry (DXA).
Results:
Mean age (±SD) was 64 (±8) years. According to urinary calcium excretion, patients were divided into normo- and hypercalciuric (HC). Of the 127 patients, 19 (15%) were classified as HC. The only difference between the groups was the age of onset of menopause (46 ± 6 vs. 50 ± 3 years HC, p < 0.0005). No association was found between calciuria and age, BMI, BMD, calcium, phosphorus, PTH, and alkaline phosphatase.
Conclusion:
HC is frequent in postmenopausal women with osteoporosis, and calciuria measurement should be included in the investigation of these patients.
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