Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy

Endoscopic Procedures III: Video Capsule Endoscopy

Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers, unexplained...

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...

Endoscopic Procedures V: ERCP

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...

Endoscopic Procedures I: Esophagogastroduodenoscopy

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Deep-learning endomicroscope with large field-of-view and depth-of-field for real-time in vivo imaging of epithelial cancer hallmarks.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Snapshot spectral fringe projection profilometry.

Applied optics·2026

Same author

Geometric phase of rotations and 3D coordinate transformations.

Journal of the Optical Society of America. A, Optics, image science, and vision·2026

Same author

Hybrid endomicroscopic objective with monolithic multi-material achromatic triplet fabricated using two-photon lithography.

Applied optics·2026

Same author

Wide spectral imaging of the rainbow from ultraviolet to infrared and locating the spectral limits of the rainbow.

Applied optics·2026

Same author

Miniature 3D-printed rod-like refractive objective for endoscopic applications.

Journal of biomedical optics·2026

Search research articles

Related Experiment Video

Updated: May 23, 2026

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

Published on: June 27, 2025

Foveated endoscopic lens.

Nathan Hagen¹, Tomasz S Tkaczyk

¹Rice University, Department of Bioengineering, Houston, Texas 77005, USA. nhagen@optics.arizona.edu

Journal of Biomedical Optics

|April 3, 2012

Summary

This study introduces a novel foveated miniature endoscopic lens. This innovative optical distortion amplifies resolution in the center, enabling detailed tissue analysis and organ navigation.

Area of Science:

Biomedical Engineering
Optical Engineering
Medical Imaging

Background:

Endoscopic procedures require high resolution for tissue analysis and a wide field of view for navigation.
Current endoscopic lenses often face a trade-off between central resolution and overall field of view.
Achieving both detailed visualization and spatial orientation within organs remains a challenge in minimally invasive surgery.

Purpose of the Study:

To develop and demonstrate a foveated miniature endoscopic lens that overcomes the resolution-field of view trade-off.
To enable simultaneous high-resolution tissue assessment and wide-field organ localization using a single endoscopic device.
To validate the performance of the foveated lens through experimental imaging.

Main Methods:

More Related Videos

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Related Experiment Videos

Last Updated: May 23, 2026

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

Published on: June 27, 2025

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Implementation of a foveated miniature endoscopic lens by amplifying optical distortion.

Integration of the foveated lens with a standard imaging fiber bundle.

Characterization of the lens's resolution and field of view using experimental setups.

Acquisition of example images and videos to showcase device capabilities.

Main Results:

The foveated lens achieves a high resolution of approximately 7-8 micrometers in the central field of view (fovea).
The system provides an overall field of view of 4.6 mm, facilitating organ localization.
Demonstrated capability to capture detailed images and videos highlighting the lens's performance.
The design successfully balances high central resolution with a broad peripheral view.

Conclusions:

The developed foveated miniature endoscopic lens effectively addresses the limitations of conventional endoscopic optics.
This technology offers a promising solution for enhanced diagnostic capabilities in minimally invasive procedures.
The proof-of-concept device demonstrates the potential for improved tissue health assessment and navigation within organs.