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Related Concept Videos

Diffusion01:21

Diffusion

Diffusion is a type of passive transport. In passive transport, a substance tends to move from an area of high concentration to an area of low concentration until the concentration is equal across the space. For example, take the diffusion of substances through the air. When someone opens a perfume bottle in a room filled with people, the perfume is at its highest concentration in the bottle and is at its lowest at the edges of the room. The perfume vapor will diffuse, or spread away, from the...
Diffusion01:12

Diffusion

Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
Protein Diffusion in the Membrane01:24

Protein Diffusion in the Membrane

Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...
Passive Diffusion: Overview and Kinetics01:17

Passive Diffusion: Overview and Kinetics

Passive diffusion is a critical process that allows small lipophilic drugs to cross the cell membrane along a concentration gradient. This mechanism's efficiency depends on four primary factors: the membrane's surface area, the drug's lipid-water partition coefficient, the concentration gradient, and the membrane's thickness.
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting their diffusion into...
Carrier Transport01:21

Carrier Transport

The generation of electrical current in semiconductors is fundamentally driven by two mechanisms: drift and diffusion. These processes are essential for the functionality and performance of semiconductor-based devices.
Drift Current:
The drift of charge carriers is started by an external electric field (E). Charged particles, such as electrons and holes, experience an acceleration between collisions with lattice atoms. For electrons, this results in a drift velocity (vd) given by:
Diffusion on Chromatography Columns01:07

Diffusion on Chromatography Columns

In column chromatography, when an analyte is introduced as a narrow band at the top of the column, the solutes begin to separate and broaden, developing a Gaussian profile. This broadening occurs due to various factors, such as longitudinal diffusion.
Longitudinal diffusion occurs when the solute molecules in the mobile phase diffuse from the more concentrated center of the chromatographic band to the more dilute regions on either side, both towards and against the flow direction. This...

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Related Experiment Video

Updated: May 23, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Diffusion in a quasi-one-dimensional system on a periodic substrate.

J C N Carvalho1, K Nelissen, W P Ferreira

  • 1Departamento de Física, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-760 Fortaleza, Ceará, Brazil. joaoclaudio@fisica.ufc.br

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|April 3, 2012
PubMed
Summary

Particle diffusion is influenced by substrate potentials and particle arrangement. Increasing substrate amplitude generally reduces diffusion, but specific configurations show enhanced diffusion and reentrant behavior due to structural changes.

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Last Updated: May 23, 2026

The Diffusion of Passive Tracers in Laminar Shear Flow
08:01

The Diffusion of Passive Tracers in Laminar Shear Flow

Published on: May 1, 2018

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells
05:56

Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells

Published on: November 12, 2020

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging
06:34

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

Published on: September 2, 2016

Area of Science:

  • Condensed matter physics
  • Statistical mechanics
  • Computational physics

Background:

  • Charged particle diffusion is crucial in various physical systems.
  • Understanding particle behavior under external potentials is key to controlling material properties.
  • Yukawa potential describes screened electrostatic interactions.

Purpose of the Study:

  • Investigate the diffusion of charged particles with Yukawa interactions.
  • Analyze the effects of parabolic confinement and periodic substrate potentials.
  • Determine how particle density, substrate amplitude, and interaction range influence diffusion.

Main Methods:

  • Langevin dynamic simulations were employed.
  • Simulations explored variations in particle density, substrate amplitude, and interaction potential range.
  • Particle configurations (single-chain vs. multichain) were examined.

Main Results:

  • Diffusion generally decreases with increasing periodic substrate potential amplitude.
  • Specific substrate potential strengths lead to increased diffusion with higher amplitude.
  • Particle arrangement significantly impacts diffusion dynamics.
  • Reentrant diffusion behavior observed for certain configurations due to structural transitions.

Conclusions:

  • Particle diffusion is complex, showing non-monotonic behavior under combined confinement and substrate potentials.
  • Structural ordering and particle arrangement play critical roles in diffusion dynamics.
  • The interplay between interparticle interactions and external potentials dictates diffusive behavior.