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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Updated: May 23, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Ashy dermatosis: a controversial entity.

Nandini Chakrabarti1, Chandan Chattopadhyay

  • 1Department of General Medicine, NRS Medical College and Hospital, 138, AJC Bose Road, Kolkata, India.

Indian Journal of Dermatology
|April 4, 2012
PubMed
Summary
This summary is machine-generated.

A rare skin condition caused diffuse darkening of the skin in a young Indian male. This case study highlights ashy dermatosis, a condition with an unknown cause.

Keywords:
Ashy dermatosisIndianSkin pigmentation

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Last Updated: May 23, 2026

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Published on: May 16, 2025

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Published on: June 10, 2025

Area of Science:

  • Dermatology
  • Internal Medicine

Background:

  • Skin hyperpigmentation can manifest in various forms.
  • Ashy dermatosis is a rare, idiopathic condition characterized by slate-gray to blue-gray skin discoloration.

Purpose of the Study:

  • To report a case of ashy dermatosis in a young Indian male.
  • To describe the clinical presentation and diagnostic considerations for this rare dermatosis.

Main Methods:

  • Clinical case presentation.
  • Review of patient's medical history and physical examination findings.

Main Results:

  • A young Indian male presented with slowly progressive, diffuse darkening of the face, arms, neck, and trunk.
  • No medications were being taken, and there was no prior history of skin disease.
  • Mucous membranes were unaffected.

Conclusions:

  • The clinical presentation is consistent with a diagnosis of ashy dermatosis.
  • The etiology of ashy dermatosis remains unknown, necessitating further research.