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Related Experiment Video

Updated: May 23, 2026

Murine Lymphocyte Labeling by 64Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT

Murine Lymphocyte Labeling by ⁶⁴Cu-Antibody Receptor Targeting for In Vivo Cell Trafficking by PET/CT

Published on: April 29, 2017

Calcified Lymph Nodes Causing Clinically Relevant Attenuation Correction Artifacts on PET/CT Imaging.

Amar Mehta¹, Ajeet Mehta, Charles Laymon

¹Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.

Journal of Radiology Case Reports

|April 4, 2012

Summary

Calcified lymph nodes can cause attenuation correction (AC) artifacts in PET/CT imaging, potentially leading to misinterpretation. Recognizing this artifact is crucial to avoid incorrect patient staging and management.

Keywords:

Artifacts Attenuation correction FDG PET PET/CT

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Novel Quantification Protocol for Cardiovascular Calcification Progression Using Longitudinal MicroPET/MicroCT Images

Novel Quantification Protocol for Cardiovascular Calcification Progression Using Longitudinal MicroPET/MicroCT Images

Published on: November 15, 2024

Area of Science:

Medical Imaging
Radiology
Nuclear Medicine

Background:

Positron Emission Tomography/Computed Tomography (PET/CT) imaging is susceptible to artifacts.
CT-based attenuation correction (AC) artifacts are common in PET/CT.
Artifacts from calcified lymph nodes are clinically significant but underreported.

Purpose of the Study:

To report cases of AC artifacts caused by calcified lymph nodes in PET/CT.
To highlight the potential for misinterpretation and mismanagement due to this artifact.

Main Methods:

Case series reporting on patients with calcified lymph nodes on PET/CT.
Analysis of three cases with AC artifacts and one without.

Main Results:

Three out of four cases demonstrated AC artifacts due to calcified lymph nodes.
These artifacts could have led to altered patient staging and management if misinterpreted as malignant.

Conclusions:

Calcified lymph nodes can cause significant AC artifacts in PET/CT.
Awareness of this artifact is essential to prevent misinterpretation and ensure appropriate patient care.