Enterococcus avium. An unusual cause of cerebral abscess
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Updated: May 23, 2026

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Published on: September 27, 2018
Abimbola O Osoba1, Hussam Kutub, Ahmed Waliuddin
1Division of Microbiology, King Khalid National Guard Hospital, PO Box 9515, Jeddah 21423, Kingdom of Saudi Arabia. Tel. +966 (2) 624000. Fax. +966 (2) 6247444.
Abstract:
Enterococci are responsible for an increasing number of human infections. They are normally part of the flora of the human gastrointestinal tract, buccal cavity, perineal skin, vagina, urethra and gallbladder, but may occur as pathogens in several sites causing urinary tract infections, intra-abdominal infections, fatal bacteremia, meningitis and endocarditis. Enterococcus avium is a rare cause of infection in humans. Here, we report a 19-year-old Saudi girl diagnosed as a case of astrocytoma grade II arising from the right thalamus. She underwent treatment with radiotherapy followed by 5 chemotherapy sessions. She subsequently developed a cerebral abscess, and we performed mini craniotomy of the left parietal region with drainage of the brain abscess. The pus obtained from the abscess grew Enterococcus avium. We successfully treated her with antibiotics and discharged her home. The rarity of the organism causing cerebral abscess has motivated the documentation of this case and the pathogenesis of Enterococcus avium.
Insights
Enterococcus avium, a rare bacterium, caused a cerebral abscess in a young woman after brain tumor treatment. Prompt antibiotic therapy led to successful recovery, highlighting this organism
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Enterococci are common human flora but increasingly cause infections.
- Enterococcus avium is an uncommon human pathogen.
- Cerebral abscesses are serious complications, often bacterial.
Purpose of the Study:
- To report a rare case of cerebral abscess caused by Enterococcus avium.
- To discuss the pathogenesis of Enterococcus avium in brain infections.
- To highlight successful treatment outcomes for this rare infection.
Main Methods:
- Case report of a 19-year-old female with astrocytoma.
- Diagnosis of cerebral abscess post-chemotherapy and radiotherapy.
- Identification of Enterococcus avium from abscess pus via culture.
- Successful treatment with antibiotics and surgical drainage.
Main Results:
- Enterococcus avium was identified as the causative agent of a cerebral abscess.
- The patient, previously treated for astrocytoma, recovered fully after treatment.
- This case underscores the potential of Enterococcus avium as a pathogen in immunocompromised individuals.
Conclusions:
- Enterococcus avium can cause severe infections like cerebral abscesses, albeit rarely.
- Early diagnosis and appropriate antibiotic treatment are crucial for favorable outcomes.
- Further research into the pathogenesis of Enterococcus avium is warranted.
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