Related Experiment Video
Updated: May 23, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Osteosarcoma of the tibia 6 years after tibial plateau leveling osteotomy
Matthew J Atherton1, Gareth Arthurs
1Small Animal Medicine and Surgery Group, The Royal Veterinary College, Hertfordshire, United Kingdom. m.atherton@vet.gla.ac.uk
Abstract:
A 7 yr old spayed female mastiff presented for examination of a left pelvic limb lameness of 3 mo duration. Six years previously, the dog had undergone tibial plateau leveling osteotomy (TPLO) surgery of the left pelvic limb for the treatment of cranial cruciate disease. On presentation, the dog had a painful and swollen proximal tibia. Following investigation, a diagnosis of osteosarcoma of the proximal left tibia at the site of the previous TPLO surgery was made. This is the first reported case of osteosarcoma following TPLO using an implant other than the Slocum plate.