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Updated: May 23, 2026

Positron Emission Tomography Using 64-Copper as a Tracer for the Study of Copper-Related Disorders
Published on: April 28, 2023
Copper in Alzheimer's disease: a meta-analysis of serum, plasma, and cerebrospinal fluid studies
Mariacarla Ventriglia1, Serena Bucossi, Valentina Panetta
1Department of Neurology, Campus Biomedico University, Rome, Italy.
Abstract:
This contribution reviews and corrects data from our previous meta-analysis, which appeared in the Journal of Alzheimer's Disease in 2011 concerning the role of copper in Alzheimer's disease. We repeated the meta-analysis after excluding four of the five studies from our laboratory to avoid possible bias in the result. In addition, we included two studies on serum copper levels in Alzheimer's disease not previously considered. The results indicate higher levels of copper in Alzheimer's disease patients than in controls, confirming our previous conclusion.
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