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18F-FDG PET/CT in a recurrent diffuse malignant peritoneal mesothelioma
Qi Cao1, Minh Lu, Jonathon Heath
1Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Clinical Nuclear Medicine
|April 6, 2012
Summary
Diagnosing recurrent malignant peritoneal mesothelioma is challenging. Positron emission tomography/computed tomography (PET/CT) imaging effectively identified diffuse peritoneal metabolic activity, aiding diagnosis in this rare cancer.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Peritoneal mesothelioma is a rare, aggressive malignancy.
- Early diagnosis is often delayed due to nonspecific initial findings.
Observation:
- A case of recurrent, biphasic, diffuse, malignant peritoneal mesothelioma presented with nonspecific abdominal CT findings.
- Endoscopy and laboratory studies were negative, complicating initial assessment.
Findings:
- Exploratory laparotomy confirmed widespread peritoneal malignancy.
- PET/CT imaging revealed diffuse increased metabolic activity throughout the peritoneum.
- PET/CT showed no evidence of thoracic or pleural involvement.
Implications:
- This case highlights the utility of PET/CT in diagnosing recurrent malignant peritoneal mesothelioma.
- PET/CT can identify characteristic metabolic patterns in the peritoneum.
- Accurate diagnosis is crucial for timely and effective treatment of peritoneal mesothelioma.
