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Updated: May 23, 2026

09:57
18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
Published on: January 11, 2020
[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET)
Xiang-Guo Li1, Sergio Dall'Angelo, Lutz F Schweiger
1University of St Andrews, School of Chemistry and Centre for Biomolecular Science, North Haugh, St Andrews, Fife KY16 9ST, UK. do1@st-andrews.ac.uk.
Abstract:
[(18)F]-5-Fluoro-5-deoxyribose ([(18)F]-FDR) conjugates much more rapidly than [(18)F]-FDG under mild reaction conditions to peptides and offers new prospects for mild and rapid bioconjugation for fluorine-18 labelling in PET imaging.
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