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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Clinical use of multifocal visual-evoked potentials in a glaucoma practice: a prospective study
Carlos Gustavo De Moraes1, Jeffrey M Liebmann, Robert Ritch
1Department of Ophthalmology, Einhorn Clinical Research Center, New York Eye and Ear Infirmary, 310 East 14th Street, New York, NY 10003, USA. demoraesmd@gmail.com
Documenta Ophthalmologica. Advances in Ophthalmology
|April 6, 2012
Summary
The multifocal visual-evoked potential (mfVEP) technique aids glaucoma diagnosis when other tests are inconclusive. This visual field testing influences clinical management and patient surveillance.
Area of Science:
- Ophthalmology
- Neuroscience
- Medical Imaging
Background:
- Glaucoma diagnosis relies on visual field testing and optic disc examination.
- Subtle visual field defects can be challenging to detect with standard automated perimetry (SAP).
- Multifocal visual-evoked potential (mfVEP) offers a detailed assessment of visual function.
Purpose of the Study:
- To evaluate the clinical utility of the multifocal visual-evoked potential (mfVEP) in a glaucoma practice.
- To assess how mfVEP results influence diagnostic and treatment decisions.
- To determine the role of mfVEP in managing glaucoma suspects and patients.
Main Methods:
- Prospective, descriptive study of 210 patients (420 eyes) over 2 years.
- Patients included glaucoma suspects, ocular hypertensives, and glaucoma patients.
- mfVEP testing was performed alongside standard automated perimetry (SAP).
Main Results:
- mfVEP identified functional loss in glaucoma suspects, leading to treatment in 68% of those with abnormal results.
- mfVEP detected abnormalities in 86% of eyes with glaucomatous optic neuropathy and SAP damage.
- In normal-tension glaucoma (NTG) patients, mfVEP confirmed central scotomata and identified defects not seen on SAP, prompting closer monitoring.
Conclusions:
- mfVEP is valuable in clinical practice when standard tests provide insufficient or conflicting information.
- mfVEP findings directly influenced clinical management decisions.
- The technique enhances patient surveillance, particularly for normal-tension glaucoma.
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