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Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Related Experiment Video

Updated: May 23, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

[Neuroimaging in pediatric epilepsy].

M Trichard1, A Léautaud, N Bednarek

  • 1Service de pédiatrie A, pôle Mère-Enfant, CHU de Reims, 47, rue Cognacq-Jay, 51092 Reims cedex, France. zion.t@wanadoo.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 7, 2012
PubMed
Summary
This summary is machine-generated.

Pediatric epilepsy has diverse causes like brain malformations and tumors. Advanced MRI techniques are crucial for diagnosing subtle lesions and guiding surgical treatment in difficult cases.

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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
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Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy

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A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Neuroradiology

Context:

  • Epilepsy in children stems from various causes including cortical malformations, phakomatosis, perinatal insults, and tumors.
  • A significant portion (25%) of pediatric epilepsy cases are pharmacoresistant, necessitating alternative treatment strategies.
  • Magnetic Resonance Imaging (MRI) is vital for identifying potential epileptogenic lesions and considering surgical interventions.

Purpose:

  • To illustrate the diverse etiologies of pediatric epilepsy through a comprehensive review of MRI findings.
  • To aid clinicians in recognizing characteristic and subtle MRI features associated with different epilepsy causes.
  • To highlight the role of advanced imaging techniques beyond conventional MRI in diagnosing pediatric epilepsy.

Summary:

  • Common pediatric epilepsy causes include cortical malformations (e.g., hemimegalencephaly, cortical dysplasia) and phakomatoses (e.g., tuberous sclerosis, neurofibromatosis).
  • Standard MRI protocols involve multiplanar sequences (T1, T2, Flair, T1 inversion-recovery, post-contrast T1) to detect epileptogenic lesions.
  • Subtle malformations and certain pathologies may require advanced MRI techniques like spectroscopy and diffusion imaging for accurate diagnosis.

Impact:

  • Improved recognition of MRI findings can lead to earlier and more accurate diagnoses of pediatric epilepsy.
  • Enhanced understanding of imaging characteristics aids in selecting appropriate patients for epilepsy surgery.
  • Integration of advanced imaging modalities can improve diagnostic yield in complex pediatric epilepsy cases.