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Updated: May 23, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
10:02

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

[Cerebral palsy--perinatal aspects]

A Nikolov, E Pavlova, N Yarukova

    Akusherstvo I Ginekologiia
    |April 10, 2012
    PubMed

    Insights

    Cerebral palsy involves motor impairments from early developmental issues. This review details its incidence, risk factors, and causes, focusing on perinatal factors.

    Area of Science:

    • Neurology
    • Developmental Pediatrics
    • Public Health

    Context:

    • Cerebral palsy (CP) presents complex motor impairments originating from early developmental anomalies.
    • CP imposes substantial emotional, financial, and social burdens on patients, families, and caregivers.
    • Understanding CP's origins is crucial for effective intervention and support.

    Purpose:

    • To review the incidence and risk factors of cerebral palsy.
    • To explore the etiopathogenesis of CP, linking it to perinatal events.
    • To highlight key aspects of perinatal cerebral palsy.

    Summary:

    • Cerebral palsy arises from non-progressive, yet evolving, motor deficits due to early fetal or childhood lesions.
    • This review examines evidence linking intrauterine infection, prematurity, asphyxia, multiple pregnancies, and assisted reproductive techniques to CP.
    • Key elements of perinatal cerebral palsy are elucidated.

    Impact:

    • Provides a comprehensive overview of cerebral palsy etiology and incidence.
    • Informs healthcare professionals and families about risk factors and developmental impacts.
    • Contributes to understanding perinatal factors influencing cerebral palsy development.

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