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The blood-brain barrier choline transporter

Werner J Geldenhuys1, David D Allen

  • 1Department of Pharmaceutical Sciences, Northeast Ohio Medical University, 4209 State Route 44, Rootstown, OH 44272, USA. wgeldenh@neomed.edu

Central Nervous System Agents in Medicinal Chemistry
|April 10, 2012
PubMed
Summary

Designing brain-penetrating drugs requires understanding the blood-brain barrier (BBB). This review details structural needs for organic cation transporters (OCTs) to improve central nervous system (CNS) drug delivery.

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