Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aging and metabolism contribute separately to brain-body health.

PLoS biology·2026
Same author

Selective molecular and network architecture features underlie brain cortical atrophy in dementia with Lewy bodies.

Journal of biomedical science·2026
Same author

Cell type transcriptomic modules reveal shared molecular mechanisms in Alzheimer's and Parkinson's disease.

GigaScience·2026
Same author

Network and receptor architectures shape brain morphometry in addiction.

medRxiv : the preprint server for health sciences·2026
Same author

Multiscale characterization of cortical signatures in positive and negative schizotypy: a worldwide ENIGMA study.

Molecular psychiatry·2026
Same author

Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer's disease.

Research square·2026

Related Experiment Video

Updated: May 23, 2026

Studying Food Reward and Motivation in Humans
12:09

Studying Food Reward and Motivation in Humans

Published on: March 19, 2014

Functional brain imaging of appetite.

Alain Dagher1

  • 1Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, Quebec, H3A 2B4, Canada. alain.dagher@mcgill.ca

Trends in Endocrinology and Metabolism: TEM
|April 10, 2012
PubMed
Summary

Obesity is a neurobehavioral disorder driven by overeating and inactivity. Brain imaging reveals how neural systems controlling appetite contribute to overeating in today's food environment.

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Public Health

Background:

  • Obesity is a complex neurobehavioral disorder stemming from overeating and physical inactivity.
  • The brain regulates food intake by integrating energy balance signals and external food cues.
  • Modern environments with abundant calorie-dense foods challenge innate appetite regulation mechanisms.

Purpose of the Study:

  • To review the application of functional brain imaging in humans to understand appetite control.
  • To explore how neural systems involved in appetite regulation contribute to obesity vulnerability.

Main Methods:

  • Review of recent human studies utilizing functional brain imaging (e.g., fMRI, PET).
  • Analysis of neuroimaging data to identify brain regions and networks involved in appetite control.

More Related Videos

Combining Quantitative Food-intake Assays and Forcibly Activating Neurons to Study Appetite in Drosophila
07:24

Combining Quantitative Food-intake Assays and Forcibly Activating Neurons to Study Appetite in Drosophila

Published on: April 24, 2018

Related Experiment Videos

Last Updated: May 23, 2026

Studying Food Reward and Motivation in Humans
12:09

Studying Food Reward and Motivation in Humans

Published on: March 19, 2014

Combining Quantitative Food-intake Assays and Forcibly Activating Neurons to Study Appetite in Drosophila
07:24

Combining Quantitative Food-intake Assays and Forcibly Activating Neurons to Study Appetite in Drosophila

Published on: April 24, 2018

  • Integration of findings with knowledge of obesogenic environmental factors.

    • Main Results:

    • Functional brain imaging has provided insights into the neural control of appetite.
    • Specific neural systems are implicated in the tendency to overeat in calorie-rich environments.
    • Understanding these neural mechanisms is key to addressing obesity.

    Conclusions:

    • The brain's central role in appetite regulation makes it a critical focus for obesity research.
    • Functional brain imaging is a valuable tool for elucidating the neurobiology of overeating.
    • Neural vulnerabilities in appetite control contribute to the obesity epidemic in modern environments.