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Facial and axillary apocrine chromhidrosis
Berta Pérez Tato1, Elena Zamora Martínez, Begoña Sánchez Albisua
1Department of Dermatology, Hospital Universitario de Móstoles, Madrid, Spain.
Dermatology Online Journal
|April 10, 2012
Summary
Apocrine chromhidrosis, a rare disorder causing pigmented sweat, was successfully treated in a patient with facial and axillary symptoms. Botulinum toxin type A offered a favorable response.
Area of Science:
- Dermatology
- Medical Case Reports
Background:
- Apocrine chromhidrosis is a rare, idiopathic condition characterized by pigmented sweat excretion.
- It typically affects apocrine glands, leading to visible discoloration.
Observation:
- A 26-year-old woman presented with a 3-year history of dark blue secretions from her malar cheeks.
- Examination revealed blue fluid expressed from follicles and subtle blue axillary discoloration.
- Histopathology showed lipofuscin granules within apocrine epithelium.
Findings:
- Diagnosis of apocrine chromhidrosis confirmed via clinical presentation and histopathology.
- Initial treatments with aluminum chloride hexahydrate and capsaicin cream were poorly tolerated.
- Botulinum toxin type A demonstrated a successful therapeutic response.
Implications:
- This case highlights botulinum toxin type A as an effective treatment for apocrine chromhidrosis.
- It expands understanding of facial and axillary involvement in this rare disorder.
- Further research into novel therapeutic strategies for chromhidrosis is warranted.
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