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Related Concept Videos

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

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Related Experiment Video

Updated: May 23, 2026

Generation of a Gene-disrupted Streptococcus mutans Strain Without Gene Cloning
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Generation of a Gene-disrupted Streptococcus mutans Strain Without Gene Cloning

Published on: October 23, 2017

PCR-Mediated Gene Disruption: One-Step Method

David C Amberg, Daniel J Burke, Jeffrey N Strathern

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    No abstract available in PubMed .

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