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Updated: May 23, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
Published on: July 1, 2013
The influence of pore size on osteoblast phenotype expression in cultures grown on porous titanium
L N Teixeira1, G E Crippa, L-P Lefebvre
1Cell Culture Laboratory, School of Dentistry of Ribeirao Preto, University of Sao Paulo, SP, Brazil.
Abstract:
This study investigated the effect of pore size on osteoblastic phenotype development in cultures grown on porous titanium (Ti). Porous Ti discs with three different pore sizes, 312 μm (Ti 312), 130 μm (Ti 130) and 62 μm (Ti 62) were fabricated using a powder metallurgy process. Osteoblastic cells obtained from human alveolar bone were cultured on porous Ti samples for periods of up to 14 days. Cell proliferation was affected by pore size at day 3 (p=0.0010), day 7 (p=0.0005) and day 10 (p=0.0090) in the following way: Ti 62
