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Related Concept Videos

Pericarditis I: Introduction01:22

Pericarditis I: Introduction

Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...

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Updated: May 23, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

The post-pericardiotomy syndrome.

Massimo Imazio1

  • 1Cardiology Department, Maria Vittoria Hospital, Torino, Italy. massimo_imazio@yahoo.it

Current Opinion in Pulmonary Medicine
|April 11, 2012
PubMed
Summary
This summary is machine-generated.

Postpericardiotomy syndrome (PPS) affects 20% of patients after cardiac surgery. Colchicine shows promise for preventing PPS and other complications, warranting further research for evidence-based strategies.

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Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
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Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Immunology

Background:

  • Postpericardiotomy syndrome (PPS) is a frequent complication after cardiac surgery.
  • Its epidemiology is poorly understood due to a lack of standardized diagnostic criteria.
  • The pathogenesis is not fully elucidated, with an immune-mediated origin not explaining all cases.

Purpose of the Study:

  • To review recent updates on the diagnosis, therapy, prognosis, and prevention of PPS.
  • To highlight the need for standardized diagnostic criteria for early recognition and treatment.
  • To explore novel therapeutic and preventive strategies for PPS.

Main Methods:

  • Literature review of recent studies on postpericardiotomy syndrome.
  • Analysis of current diagnostic, therapeutic, and preventive approaches.
  • Evaluation of the role of anti-inflammatory drugs, including colchicine.

Main Results:

  • Standardized diagnostic criteria for PPS are needed for early detection and management.
  • Current treatments rely on anti-inflammatory drugs (NSAIDs, corticosteroids).
  • Colchicine is a promising, well-tolerated agent for preventing PPS and other postoperative complications like effusions and atrial fibrillation.

Conclusions:

  • PPS impacts approximately 20% of patients post-cardiac surgery, increasing hospital stay and costs.
  • While short- to middle-term prognosis is generally good, constrictive pericarditis may occur long-term.
  • Further research into therapeutic and preventive strategies, particularly involving colchicine, is essential for evidence-based care.