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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting
1Northern Michigan University School of Nursing, Marquette, Michigan 49855, USA. rita_wickham@yahoo.com
Cancer Control : Journal of the Moffitt Cancer Center
|April 11, 2012
Summary
Chemotherapy-induced nausea and vomiting (CINV) management requires optimal antiemetic strategies. Combining standard-of-care antiemetics with corticosteroids improves patient outcomes and reduces overall treatment costs.
Area of Science:
- Oncology
- Pharmacology
Background:
- Chemotherapy-induced nausea and vomiting (CINV) significantly impacts cancer patient quality of life.
- Current antiemetic use is often suboptimal despite available effective treatments.
Purpose of the Study:
- To review CINV pathophysiology.
- To discuss effective antiemetic drug classes and cost considerations for treatment planning.
Main Methods:
- Literature review of CINV pathophysiology.
- Analysis of antiemetic drug classes and cost-effectiveness.
Main Results:
- Combination therapy with 5-hydroxytryptamine-3 receptor antagonists, neurokinin-1 receptor antagonists, and corticosteroids is highly effective.
- Older agents like prochlorperazine, metoclopramide, and olanzapine can be viable alternatives.
Conclusions:
- Standard-of-care antiemetics plus corticosteroids are recommended for CINV intervention.
- The cost of suboptimal prophylaxis and indirect costs outweigh initial antiemetic expenses.
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