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Related Experiment Video

Updated: May 23, 2026

Use of a Video Scoring Anchor for Rapid Serial Assessment of Social Communication in Toddlers
09:16

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Published on: March 14, 2018

Social preferences in Rett syndrome.

Aleksandra Djukic1, Maria Valicenti McDermott

  • 1Rett Syndrome Center, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA. adjukic@montefiore.org

Pediatric Neurology
|April 12, 2012
PubMed
Summary

Girls with Rett syndrome show social preferences, looking at people and eyes, despite communication challenges. Eye tracking reveals cognitive insights and social isolation in this rare neurodevelopmental disorder.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Genetics

Background:

  • Rett syndrome causes severe communication and motor impairments, limiting assessment.
  • Understanding nonverbal cognition and social interaction is crucial for affected children.
  • Limited research exists on the cognitive and social world of individuals with Rett syndrome.

Purpose of the Study:

  • To investigate nonverbal cognitive abilities in girls with Rett syndrome.
  • To analyze visual preferences and social attention patterns.
  • To explore the potential of eye-tracking technology for assessing cognition in Rett syndrome.

Main Methods:

  • Eye-tracking technology was used to analyze visual fixation patterns.
  • 49 girls diagnosed with Rett syndrome participated.

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  • A control group of typically developing girls was included for comparison.

    • Main Results:

    • Girls with Rett syndrome exhibited a preference for socially relevant stimuli.
    • They demonstrated increased visual attention towards people and eyes.
    • Eye-tracking data provided insights into their cognitive processing and social engagement.

    Conclusions:

    • Eye tracking is a viable method for assessing cognition in Rett syndrome.
    • Individuals with Rett syndrome possess social preferences despite motor and communication deficits.
    • Findings highlight the potential mismatch between social desires and functional abilities, contributing to isolation.