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Updated: May 23, 2026

Lens Transplantation in Zebrafish and its Application in the Analysis of Eye Mutants
Published on: June 1, 2009
[Zebrafish-a new animal models of anterior segment embryonic development and diseases basic research]
Yong-na Hao1, Rui-hua Wei, Shao-zhen Zhao
1The Eye Center of Tianjin Medical University, Tianjin 300070, China.
Abstract:
In recent years, zebrafish has become ideal animal models of human disease with its unique characteristics, such as small body, fecundity, fast development and growth, embryo transparency, and so on. Furthermore, the structure and gene of zebrafish eye are highly conservative with human eye, which make ophthalmologists to pay close attention to zebrafish. This review focus on the studies and applications on zebrafish embryonic development of anterior segment, including the morphogenesis of cornea, lens and anterior chamber, and diseases of anterior segment (corneal diseases, cataract, glaucoma).

