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Distributed and grid computing projects with research focus in human health.

Marianna Diomidous1, Dimitrios Zikos

  • 1Dept. of Public Health, Faculty of Nursing, University of Athens, Greece. mdiomidi@nurs.uoa.gr

Studies in Health Technology and Informatics
|April 12, 2012
PubMed
Summary

Large-scale distributed and grid computing projects leverage internet-connected computers for human health research. These projects focus on molecular biology, aiding in disease cure discovery and drug design.

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Area of Science:

  • Computational Biology
  • Bioinformatics
  • Distributed Computing

Background:

  • Distributed and grid computing systems enhance performance by connecting multiple computers.
  • The World Wide Web enables aggregation of individual CPU power for research.
  • Numerous large-scale projects utilize these systems for scientific advancement.

Purpose of the Study:

  • To identify and present active, large-scale distributed and grid computing projects focused on human health research.
  • To highlight the research areas and target diseases of these projects.
  • To emphasize the need for increased citizen participation and collaboration.

Main Methods:

  • Systematic identification of active distributed and grid computing projects.
  • Filtering projects based on scale (over 2000 Processing Units).
  • Analysis of research focus, particularly in molecular biology and disease-related areas.

Main Results:

  • Eleven active projects with over 2000 Processing Units each were identified.
  • Primary research areas include protein structure prediction, genomic analysis, and drug design.
  • Target diseases span HIV, cancer, influenza, Alzheimer's, and more.

Conclusions:

  • Large-scale distributed computing is crucial for advancing human health research.
  • Molecular biology applications are dominant, driving progress in disease understanding and treatment.
  • Enhanced national and international collaboration, alongside public engagement, is vital for future success.