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Updated: May 23, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
[Metabolic changes in prepuberty children with extrauterine growth restriction]
M Ortiz Espejo1, M Gil Campos, M C Muñoz Villanueva
1Unidad de Metabolismo e Investigación Pediátrica, Hospital Universitario Reina Sofía, Córdoba, España.
Children with extrauterine growth restriction (EUGR) show significant anthropometric, blood pressure, and metabolic changes in prepuberty. Early nutritional monitoring and long-term follow-up are crucial for managing these growth and metabolic alterations.
Area of Science:
- Pediatric Endocrinology
- Neonatal Nutrition
- Growth and Development
Context:
- Extrauterine growth restriction (EUGR) in infancy is linked to nutritional deficits.
- These deficits may predispose children to metabolic issues later in life, similar to intrauterine growth restriction.
Purpose:
- To investigate anthropometric, blood pressure, and metabolic profiles in prepubertal children with a history of EUGR.
- To compare these parameters with a control group of healthy children.
Summary:
- Prepubertal children with EUGR exhibited significantly lower height and BMI, and higher systolic and diastolic blood pressure compared to controls.
- The EUGR group also showed higher glucose levels and lower HDL cholesterol, though not clinically significant.
Impact:
- Identifies key health alterations in children with EUGR during prepuberty.
- Highlights the need for optimized perinatal nutrition and continued pediatric follow-up to mitigate long-term health risks associated with EUGR.
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