Related Experiment Video
Updated: May 23, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
One-stop evaluation of globus pharyngeus symptoms with transnasal esophagoscopy and swallowing function test
Michael C F Tong1, Han Gao, Janice S C Lin
1Department of Otorhinolaryngology, Head and Neck Surgery and Institute of Human Communicative Research, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China. mtong@cuhk.edu.hk
Objective:
To evaluate the feasibility of a one-stop assessment of patients complaining of globus sensation with transnasal esophagoscopy (TNE) and functional endoscopic evaluation of swallowing (FEES).
Design:
Prospective, nonrandomized, experimental investigation.
Setting:
Tertiary referral centre.
Methods:
Sixty-three consecutive patients complaining of a lump in the throat were evaluated by this combined approach.
Main Outcome Measures:
The safety and feasibility of performing a one-stop TNE plus FEES were explored by subjective measurement of the patients' tolerance and satisfaction and comments from surgeons. The possible therapeutic effects were also assessed 2 months after the procedure.
Results:
All 63 patients completed the TNE and FEES without any complications. The average duration of the examination was 6.27 ± 2.52 (95% CI 5.63-6.91) minutes. The findings included arytenoid cyst, epiglottic cyst, vocal cord nodules, vocal cord palsy, esophageal reflux, and foveolar gland hyperplasia. Two patients (3.2%) demonstrated some degree of fluid penetration or aspiration. Nine specialists all scored highly on a visual analogue scale on the manipulation, visualization, and satisfaction of the TNE procedure (median = 8 of 10). Patients also rated a low pain score (median = 1 of 10) and a high satisfaction score (median = 9 of 10).
Conclusion:
The combined technique of TNE and FEES can be used safely as a one-stop examination tool for patients with globus pharyngeus symptoms.
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