Related Experiment Video
Updated: May 23, 2026

10:42
Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
Published on: May 12, 2023
Stereocontrolled access to optically-enriched oxabispidines
Heloise Brice1, Duncan M Gill, Laura Goldie
1Pharmaceutical Development, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough LE11 5RH, UK.
Abstract:
A range of chiral, optically-enriched bicyclic oxabispidines were prepared from (S)-(-)-2,3-epoxypropylphthalimide using an efficient sequence featuring a stereocontrolled intramolecular Mannich reaction as the key transformation.

