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Plasmablastic extramedullary plasmacytoma
Irulandy Ponniah1, Suhasini Rajan
1Department of Oral and Maxillofacial Pathology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India. salivaryduct@yahoo.co.uk
Indian Journal of Pathology & Microbiology
|April 14, 2012
Summary
Extramedullary plasmacytoma is a rare soft tissue tumor. This case highlights the diagnostic challenges and successful radiotherapy treatment of a plasmablastic variant in the gingiva.
Area of Science:
- Oncology
- Pathology
Background:
- Extramedullary plasmacytoma (EMP) is a plasma cell neoplasm occurring outside bone marrow.
- Distinguishing EMP from other plasma cell disorders and lymphomas can be challenging due to overlapping features.
Observation:
- A case of plasmablastic extramedullary plasmacytoma in a 52-year-old patient's mandibular lingual gingiva is presented.
- The lesion exhibited morphological and immunohistochemical similarities to plasmablastic lymphoma, complicating diagnosis.
Findings:
- The diagnosis of plasmablastic extramedullary plasmacytoma was established.
- The gingival mass showed significant regression following primary radiotherapy.
Implications:
- This case underscores the importance of considering plasmablastic extramedullary plasmacytoma in the differential diagnosis of gingival masses.
- Radiotherapy can be an effective treatment modality for localized plasmablastic extramedullary plasmacytoma.
