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Related Concept Videos

Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Dosage Regimen: Fixed Dose01:01

Dosage Regimen: Fixed Dose

Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...

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Medication adherence to multidrug regimens.

Zachary A Marcum1, Walid F Gellad

  • 1Department of Medicine (Geriatrics), School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

Clinics in Geriatric Medicine
|April 17, 2012
PubMed
Summary
This summary is machine-generated.

Medication adherence remains poorly understood despite extensive research. More studies are needed to develop effective interventions that improve medication adherence and health outcomes, especially for older adults.

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Area of Science:

  • Gerontology
  • Health Behavior Research
  • Clinical Pharmacy

Background:

  • Medication adherence is a critical factor in health outcomes, particularly for older adults.
  • Despite decades of research, the factors influencing medication adherence are not fully understood.
  • Current understanding of medication adherence is limited, highlighting a significant gap in health behavior research.

Purpose of the Study:

  • To emphasize the persistent challenge in understanding medication adherence.
  • To highlight the critical need for future research in medication adherence.
  • To underscore the importance of translating research into clinical practice for older adults.

Main Methods:

  • Literature review and synthesis of existing research on medication adherence.
  • Analysis of historical perspectives on patient compliance and adherence.
  • Identification of research gaps in understanding and improving medication adherence.

Main Results:

  • Medication adherence is extensively documented but remains poorly understood, a paradox noted over 35 years ago.
  • There is a significant lack of effective, translated interventions to improve medication adherence in clinical practice.
  • The health of older adults is directly impacted by suboptimal medication use processes.

Conclusions:

  • Further research is essential to elucidate the complexities of medication adherence.
  • Translating research findings into practical interventions is crucial for clinical implementation.
  • Improving medication adherence is key to enhancing health outcomes for the aging population.