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Updated: May 23, 2026
06:43
Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
Published on: December 7, 2013
Coronary atherosclerosis -- a postmortem histopathological study.
S Kumar1, Verma A Kumar, N Kumar
1Department of Forensic Medicine and Toxicology, B.R.D. Medical College, Gorakhpur (U.P.), India.
Bratislavske Lekarske Listy
|April 17, 2012
Summary
Coronary atherosclerosis, a common finding in autopsy studies, affects major coronary arteries. Indians show a higher prevalence, possibly linked to lifestyle changes and risk factors.
Area of Science:
- Cardiovascular Pathology
- Atherosclerosis Research
Background:
- Cardiovascular disease, particularly coronary heart disease, is a primary cause of death in developed nations.
- Understanding coronary atherosclerosis prevalence and characteristics is crucial for public health.
Purpose of the Study:
- To determine the prevalence, severity, and location of coronary atherosclerosis in postmortem hearts.
- To compare findings with existing literature and explore potential ethnic variations.
Main Methods:
- Autopsy examination of coronary arteries from 50 individuals aged 30-60 years.
- Gross and microscopic inspection of coronary arteries for pathological lesions.
Main Results:
- Coronary atherosclerosis was present in 80% of cases; 20% showed no lesions.
- The Left Anterior Descending artery had the highest lesion distribution (68%), followed by the Right Coronary Artery (50%) and Left Circumflex (36%).
- Proximal involvement was most common, except for distal involvement in the Right Coronary Artery.
Conclusions:
- The study confirms a significant prevalence of coronary atherosclerosis in the studied population.
- A higher prevalence in Indians suggests a potential link to lifestyle factors and risk factors.
- Findings align with other autopsy-based studies on coronary atherosclerosis.
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