Related Experiment Video
Updated: May 23, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
Parathyroid cysts: a clinical and radiological challenge
Jolene Witherspoon1, Michael Lewis
1ST6 in General Surgery, Princess of Wales Hospital, Bridgend CF31 1RQ. jolene.witherspoon@wales.nhs.uk
Parathyroid cysts are rare neck swellings. This case highlights that a presumed thyroid cyst can be parathyroid in origin, crucial for accurate diagnosis and treatment.
Area of Science:
- Endocrinology
- Surgical Pathology
Background:
- Parathyroid cysts are uncommon, representing 0.6% of thyroid and parathyroid lesions.
- These cysts can be functional, secreting parathyroid hormone, or non-functional.
- Non-functional cysts may cause cosmetic concerns or compressive symptoms like dysphagia, dyspnea, or recurrent laryngeal nerve palsy.
Observation:
- A young woman presented with a neck swelling initially diagnosed as a thyroid cyst via examination and imaging.
- The clinical presentation suggested a common thyroid lesion.
Findings:
- Histopathological examination revealed the neck swelling to be of parathyroid origin, not thyroid.
- This underscores the importance of considering parathyroid cysts in the differential diagnosis of neck masses.
Implications:
- Accurate differentiation between thyroid and parathyroid cysts is essential for appropriate patient management.
- This case emphasizes the need for considering rare diagnoses in neck swellings, even when initial findings suggest a more common etiology.
Related Concept Videos
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Urinary Tract Calculi III: Medical Management
Urinary Tract Calculi VI: Surgical Management
Urologic Endoscopic Procedure: Cystoscopic Examination
