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[Secondary amyloidosis and rapidly progressing renal insufficiency. A clinico-pathologic study]
A Segarra Medrano1, J L Tovar Méndez, M T Vidal
1Servicio de Nefrología, Hospital General Vall d'Hebron, Barcelona.
Medicina Clinica
|June 23, 1990
Abstract:
In the present study, 7 patients with secondary amyloidosis and renal involvement who developed rapidly progressive deterioration of renal function are reported. After the investigation of the possibly implicated clinicopathological factors a cause was found for 3 patients. In the remaining 4 patients, the rapid evolution to end stage renal disease was attributable to the rapid progression of amyloid deposits by itself. A correlation between the evolution of renal function, vascular amyloid deposits and interstitial fibrosis is reported.