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Related Concept Videos

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Hyperosmolar Hyperglycemic State

Hyperosmolar Hyperglycemic State, or HHS, is a serious and life-threatening complication of type 2 diabetes mellitus. It is characterized by three main features: severe hyperglycemia, profound dehydration, and elevated serum osmolality, all occurring without significant ketoacidosis.HHS typically develops in older adults or individuals with limited access to fluids. This may result from illness, cognitive impairment, or medications such as diuretics or corticosteroids. These factors reduce...
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Related Experiment Video

Updated: May 23, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

[HELLP syndrome--severe complication during pregnancy].

Jouni Ahonen1, Mika Nuutila

  • 1HUS, naistenklinikka.

Duodecim; Laaketieteellinen Aikakauskirja
|April 18, 2012
PubMed
Summary
This summary is machine-generated.

HELLP syndrome, a pregnancy complication causing hemolysis, elevated liver enzymes, and low platelets, significantly increases maternal risks. Early diagnosis and termination of pregnancy are crucial for managing this severe condition.

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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Published on: January 26, 2024

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Critical Care Medicine

Context:

  • HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) is a severe pregnancy complication.
  • It involves microcirculatory disturbance and is often associated with pre-eclampsia, but can occur independently.
  • This condition leads to increased maternal morbidity and mortality.

Purpose:

  • To summarize the key aspects of HELLP syndrome.
  • To highlight its severe complications and management.
  • To emphasize the critical nature of this obstetric emergency.

Summary:

  • HELLP syndrome is characterized by hemolysis, elevated liver enzymes, and low platelets.
  • Complications include coagulation disorders, organ failure (renal, hepatic, respiratory), CNS symptoms, infections, and placental abruption.
  • The only definitive treatment during pregnancy is termination of the pregnancy.

Impact:

  • Increased awareness of HELLP syndrome's severity and potential complications.
  • Underscores the critical need for timely diagnosis and intervention in obstetric care.
  • Highlights termination of pregnancy as the primary treatment strategy for maternal survival.