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Modified Shapiro reactions with bismesitylmagnesium as an efficient base reagent

William J Kerr1, Angus J Morrison, Marek Pazicky

  • 1Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, G1 1XL, Scotland, UK. w.kerr@strath.ac.uk

Organic Letters
|April 18, 2012
PubMed
Summary

Bismesitylmagnesium effectively mediates the Shapiro reaction for synthesizing functionalized styrenes from tosylhydrazones. This magnesium-based method provides high yields and electrophile incorporation, offering an efficient alternative to traditional lithium reagents.

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