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Renal health and the environment: heavy metal nephrotoxicity
Ernesto Sabath1, M Ludivina Robles-Osorio
1Departamento de Nefrología, Hospital General de Querétaro, México. esabath@yahoo.com
Abstract:
We currently recognise that environmental toxins such as cadmium, lead, and arsenic play a significant role in the development of chronic renal failure. Epidemiological studies have shown a strong association between exposure to these metals and the presence of chronic kidney injury. The physiopathological mechanisms behind metal-induced kidney injury are complex, and some aspects of their metabolism and damage mechanisms remain unknown. This review aims to analyse the physiopathological mechanisms of kidney injury due to cadmium, lead and arsenic.
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