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Updated: May 23, 2026
07:04
Creation of Two Saccular Elastase-Digested Aneurysms with Different Hemodynamics in One Rabbit
Published on: April 15, 2021
Flow diverters and a tale of two aneurysms
Gregory A Kuzmik1, Theresa Williamson, Asiri Ediriwickrema
1Yale University School of Medicine, New Haven, Connecticut 06520, USA.
Journal of Neurointerventional Surgery
|April 19, 2012
Summary
Flow-diverting devices show promise for treating large brain aneurysms. However, unpredictable delayed complications like hemorrhage can occur even after successful device placement, necessitating caution.
Area of Science:
- Neurosurgery
- Interventional Neuroradiology
- Vascular Neurology
Background:
- Large and giant intracranial aneurysms pose significant treatment challenges.
- Flow-diverting devices (FDDs) have emerged as a novel therapeutic option.
- The safety and efficacy of FDDs, particularly regarding delayed complications, require further investigation.
Observation:
- Two patients with symptomatic giant paraclinoid internal carotid artery aneurysms were treated with SILK flow-diverting devices.
- Both procedures were technically uncomplicated.
- One patient achieved complete aneurysm occlusion and remained well at 1 year.
Findings:
- The second patient experienced a delayed subarachnoid hemorrhage.
- This occurred despite initial successful reduction in aneurysm filling post-FDD placement.
- Outcomes can vary significantly even with similar aneurysm presentations and treatment.
Implications:
- Flow-diverting devices offer a valuable alternative for complex aneurysms.
- The risk of delayed aneurysmal rupture and hemorrhage following FDD placement is not fully understood.
- Careful patient selection and long-term monitoring are crucial due to the unpredictable nature of FDDs.
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