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Updated: May 23, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

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Published on: July 13, 2019

Effectiveness of stepwise interventions targeted to decrease central catheter-associated bloodstream infections.

L Silvia Munoz-Price¹, Cameron Dezfulian, Mary Wyckoff

¹Department of Medicine, Division of Biostatistics, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA. smunozprice@med.miami.edu

Critical Care Medicine

|April 19, 2012

Summary

This summary is machine-generated.

Implementing chlorhexidine daily baths and "scrub-the-hub" significantly reduced central catheter-associated bloodstream infections in surgical intensive care units. These interventions demonstrate effectiveness in preventing hospital-acquired infections.

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Area of Science:

Infection Control
Healthcare Quality Improvement
Patient Safety

Background:

Central catheter-associated bloodstream infections (CABSIs) are a significant cause of morbidity and mortality in intensive care units.
Effective strategies are needed to reduce the incidence of CABSIs.

Purpose of the Study:

To evaluate the impact of three stepwise interventions on reducing CABSIs in surgical intensive care units.
To assess the effectiveness of chlorhexidine interventions and nursing compliance checks.

Main Methods:

A quasi-experimental study was conducted in three surgical intensive care units.
Interventions included chlorhexidine "scrub-the-hub," daily chlorhexidine baths, and compliance monitoring with a checklist.
Data on CABSIs were collected over 33 months.

Main Results:

A progressive reduction in CABSIs was observed across all three units following intervention implementation.
Chlorhexidine daily baths showed a particularly notable decrease in infection rates.
Specific rate reductions were observed in unit A (8.6 to 0.5), unit B (6.9 to 1.6), and unit C (7.8 to 0.6).

Conclusions:

Stepwise implementation of chlorhexidine "scrub-the-hub" and daily baths effectively reduced CABSIs in surgical ICUs.
These interventions represent a successful strategy for improving patient safety and reducing healthcare-associated infections.