Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Visual Detection of Cumulative Exposure to Amines by Controlling the Fate of the Excited State of Photochromic Dithienylethenes.

The Journal of organic chemistry·2025
Same author

Surface photosterilization of implantable silicone biomaterials: structural and functional characterization.

Colloids and surfaces. B, Biointerfaces·2023
Same author

Photothermal release of an encapsulated therapeutic agent from polymer-wrapped gold nanoparticles.

Nanoscale advances·2022
Same author

A dual-mode visual detector for toxic hydrazine.

RSC advances·2022
Same author

Milling of poorly soluble crystalline drug compounds to generate appropriate particle sizes for inhaled sustained drug delivery.

International journal of pharmaceutics·2020
Same author

Probing the Microenvironments in a Polymer-Wrapped Core-Shell Nanoassembly Using Pyrene Chromophores.

ACS omega·2019

Related Experiment Video

Updated: May 23, 2026

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

Multimodal fluorescence modulation using molecular photoswitches and upconverting nanoparticles.

Carl-Johan Carling1, John-Christopher Boyer, Neil R Branda

  • 14D LABS, Department of Chemistry, Simon Fraser University, 8888 University Drive, Burnaby, BC, Canada.

Organic & Biomolecular Chemistry
|April 20, 2012
PubMed
Summary

Researchers controlled light emission from upconverting nanoparticles using photoresponsive dithienylethene ligands. Selective ligand activation enabled multimodal light read-out, offering tunable optical properties.

More Related Videos

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
11:20

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation

Published on: August 30, 2017

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Related Experiment Videos

Last Updated: May 23, 2026

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles
12:51

A 'Plug and Play' Method to Create Water-dispersible Nanoassemblies Containing an Amphiphilic Polymer, Organic Dyes and Upconverting Nanoparticles

Published on: November 14, 2015

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
11:20

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation

Published on: August 30, 2017

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Area of Science:

  • Materials Science
  • Nanotechnology
  • Photochemistry

Background:

  • Upconverting nanoparticles (UCNPs) offer unique optical properties for various applications.
  • Controlling UCNP emission intensity and color is crucial for advanced functionalities.
  • Photoresponsive molecules can modulate material properties upon light irradiation.

Purpose of the Study:

  • To demonstrate the control of light emission from UCNPs using surface-decorated photoresponsive ligands.
  • To investigate the effect of dithienylethene ligand activation on UCNP optical output.
  • To achieve a multimodal read-out system by selectively activating ligands in a mixed system.

Main Methods:

  • Synthesis and surface functionalization of upconverting nanoparticles with dithienylethene ligands.
  • Selective photo-switching of dithienylethene ligands using specific wavelengths of light.
  • Spectroscopic analysis to characterize the emitted light's intensity and color modulation.

Main Results:

  • The emission intensity and color of UCNPs were successfully tuned by altering the state of the dithienylethene ligands.
  • Selective activation of one or both ligands in a three-component system resulted in distinct optical responses.
  • A multimodal read-out of the emitted light was achieved, demonstrating tunable optical properties.

Conclusions:

  • Photoresponsive dithienylethene ligands provide effective external control over UCNP luminescence.
  • This approach enables the development of switchable and tunable optical materials.
  • The multimodal read-out capability opens possibilities for advanced sensing and display technologies.