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04:18
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
[Epidemiology of preterm births]
1Inserm, UMR S 953, unité de recherche épidémiologique en santé périnatale et santé des femmes et des enfants, hôpital Tenon, AP-HP, 75020 Paris. pierre-yves.ancel@inserm.fr
La Revue Du Praticien
|April 21, 2012
Summary
Preterm birth impacts many infants, increasing risks for developmental issues and disabilities. Careful monitoring of preterm infants is crucial for early detection and management of neurodevelopmental impairments.
Area of Science:
- Neonatology
- Developmental Pediatrics
- Public Health
Context:
- Preterm birth rates vary globally, with significant incidence in the USA (12-13%) and Europe (5-7%).
- In France, 1.5% of births are before 32 weeks, 0.8% at 32-33 weeks, and 5% between 34-36 weeks.
- Preterm birth is associated with increased neonatal mortality and higher risks of motor and cognitive deficiencies.
Purpose:
- To highlight the significant impact of preterm birth on infant health and development.
- To emphasize the need for vigilant monitoring of preterm infants for neurodevelopmental impairments.
- To underscore the necessity for further research into preterm birth pathophysiology and therapeutic strategies.
Summary:
- Preterm birth contributes to 50% of perinatal disabilities, affecting approximately 3,500 children annually in France.
- Neonatal mortality rates are substantially higher for very preterm (10%), moderate preterm (2-3%), and late preterm (0.5-1%) infants.
- Children born preterm face elevated risks of motor (up to 10%) and cognitive (up to 15%) deficiencies compared to full-term infants.
Impact:
- Preterm birth is a leading cause of infant mortality and long-term disabilities.
- Early detection and management of neurodevelopmental impairments in preterm infants are critical.
- Further research is essential to understand preterm birth and develop effective interventions.
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