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Nevoid hyperkeratosis of the areola misinterpreted as mycosis fungoides
Ilana S Rosman1, Donna M Hepper, Anne C Lind
1Division of Dermatology, Washington University School of Medicine, St. Louis, MO, USA.
Abstract:
Nevoid hyperkeratosis of the nipple and areola is a benign condition with fewer than 70 cases reported in the literature. We report a case of unilateral nevoid hyperkeratosis of the areola with intraepidermal lymphocytes that resembled Pautrier's microabscesses on histological examination. This is the third report of mycosis fungoides-like changes in nevoid hyperkeratosis of the nipple and areola. In addition, this is the first case to present immunohistochemical and T-cell gene rearrangement studies of the intraepidermal lymphocytes. This case highlights a potential histopathological pitfall in the diagnosis of nevoid hyperkeratosis of the nipple and areola.
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