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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Cotranslational Protein Translocation01:20

Cotranslational Protein Translocation

Translocation of proteins across membranes is an ancient process that occurs even in bacteria and archaebacteria. In fact, the components of the translocation machinery are still conserved between prokaryotes and eukaryotes.
Sec61 channel partners for cotranslational translocation
During cotranslational translocation, the Sec61 channel partners with the signal recognition particle (SRP), the signal recognition particle receptor (SR), and the ribosomes to transport the nascent polypeptide chain...
Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique helps...
Translational Regulation01:29

Translational Regulation

Translational regulation in prokaryotes ensures efficient protein synthesis by controlling ribosome access to mRNA. This regulation is mediated by secondary RNA structures, including translational riboswitches, RNA thermometers, and small RNAs (sRNAs), which respond to intracellular and environmental signals to modulate gene expression.Translational RiboswitchesRiboswitches in the leader region of mRNAs can regulate translation by altering the accessibility of the Shine-Dalgarno (SD) sequence,...
Protein Transport to the Stroma01:24

Protein Transport to the Stroma

Chloroplasts are triple membrane structures with an outer membrane, an inner membrane, and a thylakoid membrane, each containing distinct metabolite transporters, membrane translocons, and enzymes. Appropriate sorting and translocating these proteins to their correct membrane systems is essential for chloroplast function.
Protein complexes called the translocon of the outer chloroplast membrane or TOC complex, and the translocon of the inner chloroplast membrane or TIC complex mediate the...
Protein Transport to the Inner Chloroplast Membrane01:18

Protein Transport to the Inner Chloroplast Membrane

Proteins targeted to the inner chloroplast membrane, or plastid proteins, are transported by two general pathways: the stop-transfer and the re-insertion or post-import pathways. Most plastid proteins carry N-terminal transit sequences and internal import sequences targeting it to the specific chloroplast subcompartment. Proteins targeted by the stop-transfer pathway have internal hydrophobic sequences that inhibit their translocation into the stroma. As a result, these precursors are arrested...

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Updated: May 23, 2026

An Easy Method for Plant Polysome Profiling
11:09

An Easy Method for Plant Polysome Profiling

Published on: August 28, 2016

Translational plant proteomics: a perspective.

Ganesh Kumar Agrawal1, Romina Pedreschi, Bronwyn J Barkla

  • 1Research Laboratory for Biotechnology and Biochemistry, Kathmandu, Nepal. gkagrawal123@gmail.com

Journal of Proteomics
|April 21, 2012
PubMed
Summary
This summary is machine-generated.

Translational plant proteomics bridges basic science and field applications for plant value, food security, and sustainability. This review highlights decade progress and calls for better information dissemination in plant proteomics.

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Last Updated: May 23, 2026

An Easy Method for Plant Polysome Profiling
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Published on: August 28, 2016

mRNA Interactome Capture from Plant Protoplasts
12:29

mRNA Interactome Capture from Plant Protoplasts

Published on: July 28, 2017

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07:02

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Area of Science:

  • Biological Sciences
  • Proteomics
  • Plant Science

Background:

  • Translational proteomics is an emerging sub-discipline.
  • Translational plant proteomics integrates basic science for field applications.
  • Addresses plant value, food security, safety, and energy sustainability.

Purpose of the Study:

  • Review substantial progress in plant proteomics over the past decade.
  • Highlight the foundation laid for translational plant proteomics.
  • Emphasize the need for broader dissemination of plant proteomics knowledge.

Main Methods:

  • Review of recent advancements in plant proteomics.
  • Analysis of applications in model and non-model plants.
  • Exploration of proteogenomics, crop improvement, and food analysis.

Main Results:

  • Significant progress in plant proteomics over the last decade.
  • Expansion of proteomics knowledge beyond model plants.
  • Identification of diverse applications including crop improvement and food safety.

Conclusions:

  • Translational plant proteomics is well-positioned for significant impact.
  • Further research and application in plant science are expanding.
  • Enhanced dissemination channels are crucial for the scientific community.