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Published on: August 28, 2020
[Female overactive bladder syndrome and autonomic nervous system]
K Hubeaux1, M Jousse, G Amarenco
1Service de rééducation neurologique et explorations fonctionnelles, centre de Perharidy, presqu'ile de Perharidy, 29684 Roscoff, France. katelyne.hubeaux@free.fr
Summary
This review suggests that women with overactive bladder syndrome may have autonomic nervous system dysfunction, specifically a sympathetic nervous system imbalance. Further research is needed to confirm this link in overactive bladder syndrome.
Area of Science:
- Urology
- Neuroscience
- Cardiology
Background:
- Overactive bladder syndrome (OAS) is a common condition in women.
- The role of the autonomic nervous system (ANS) in OAS pathophysiology is not fully understood.
Purpose of the Study:
- To investigate the hypothesis of ANS dysfunction in female idiopathic overactive bladder syndrome.
- To review existing literature on the association between OAS and ANS markers.
Main Methods:
- Systematic literature review of studies published in PubMed, Medline, and Cochrane databases.
- Included studies focused on women with overactive bladder syndrome and autonomic nervous system assessments, such as heart rate variability (HRV) and cardiovascular tests.
- Keywords used: overactive bladder syndrome, female urinary incontinence, urge incontinence, autonomic nervous system.
Main Results:
- Women with overactive bladder syndrome showed decreased heart rate variability parameters compared to controls.
- Evidence suggests a relative increase in sympathetic tone in women with overactive bladder syndrome.
- Sympathetic cardiovascular tests were more frequently abnormal in women with overactive bladder syndrome.
Conclusions:
- The reviewed studies indicate a potential sympathetic dysfunction of the autonomic nervous system in female overactive bladder syndrome.
- Methodological variability and small study populations limit the ability to establish a definitive pathophysiological link.
- Further well-designed studies are required to confirm the role of ANS dysfunction in overactive bladder syndrome.
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