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Functionalized Fe3O4 nanoparticles for detecting zinc ions in living cells and their cytotoxicity
Gyusik Kang1, Hyunjong Son, Jung Mi Lim
1Department of Chemistry and Research Institute of Natural Sciences Gyeongsang National University, Jinju 660-701, Korea.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|April 21, 2012
Abstract:
The zinc tank: A new fluoro-chromogenic chemosensor based on BODIPY-functionalized Fe(3)O(4) nanoparticles (1) has been prepared. Chemoprobe 1 exhibits high selectivity for Zn(2+) over other competing metal ions tested. Moreover, confocal microscopy experiments established that 1 can be used for detecting Zn(2+) levels in living cells (see figure).
