Related Experiment Video
Updated: May 23, 2026

11:27
A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
Published on: April 7, 2023
[Treatment of preterm delivery--therapeutic algorithm].
Summary
This study introduces a new algorithm for preterm delivery prevention, significantly prolonging pregnancies. The enhanced protocol, including progesterone, demonstrated high success rates in delaying birth and improving outcomes.
Area of Science:
- Obstetrics and Gynecology
- Perinatology
- Maternal-Fetal Medicine
Context:
- Preterm delivery rates remain high despite advances in therapeutic management.
- Effective prevention strategies are crucial for improving neonatal and maternal outcomes.
- Current treatment protocols require optimization to address persistent preterm birth challenges.
Purpose:
- To present a novel therapeutic algorithm for the prevention of preterm delivery.
- To evaluate the efficacy of incorporating progesterone into standard preterm labor management.
- To share a clinical protocol aimed at significantly reducing the incidence of early births.
Summary:
- A clinical trial involving 23 patients diagnosed with preterm delivery (26-36 weeks gestation) was conducted.
- The algorithm included magnesium, B2-mimetics, Utrogestan, calcium channel blockers, indomethacin, and a novel progesterone regimen.
- Pregnant women under 35 weeks also received steroids for neonatal respiratory distress syndrome (RDS) prevention and Ambroxol.
Impact:
- The algorithm successfully prolonged pregnancy by over 14 days in 82.6% of cases.
- Significant postponements of delivery were observed across various durations, including over 21 days in 26.1% of patients.
- The inclusion of progesterone in the therapeutic scheme proved effective in significantly prolonging gestation.
