Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Disseminated cutaneous leiomyomas].

L Pissoat1, M Megahed

  • 1Klinik für Dermatologie und Allergologie, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Deutschland. lpissoat@ukaachen.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|April 25, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Advanced hybrid nanocomposites for infrastructure renewal: enhanced shear and flexural performance in load-bearing applications.

Scientific reports·2026
Same author

Effect of infill parameters and thermal annealing on the mechanical behavior of FDM 3D-printed polymer.

Scientific reports·2026
Same author

Insights into particle dispersion and damage mechanisms in functionally graded metal matrix composites with random microstructure-based finite element model.

Scientific reports·2024
Same author

Characterization of steel lined with multilayer micro/nano-polymeric composites.

Scientific reports·2022
Same author

Characterization and performance evaluation of Cu-based/TiO<sub>2</sub> nano composites.

Scientific reports·2022
Same author

[Lichenoid drug reactions].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2018
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Disseminated cutaneous leiomyomas are benign smooth muscle tumors. Pharmacologic antidepressant treatment effectively reduced pain in a patient with widespread skin lesions where surgery was not an option.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Cutaneous leiomyomas are benign smooth muscle neoplasms originating from piloerector muscles, vascular smooth muscle, or genital smooth muscle.
  • These tumors typically manifest between the first and third decades of life.
  • Three distinct subtypes exist: piloleiomyoma, angioleiomyoma, and genital leiomyoma.

Observation:

  • A 56-year-old woman presented with multiple, painful, red-brown papules and nodules on her trunk.
  • Clinical examination and subsequent histological analysis confirmed the diagnosis of disseminated cutaneous leiomyomas.
  • The widespread nature of the lesions precluded surgical intervention.

Findings:

  • Pharmacologic antidepressant therapy was initiated as a treatment modality for pain management.

Related Experiment Videos

  • The patient reported significant reduction in pain following the antidepressant treatment.

    • Implications:

    • This case highlights a potential therapeutic strategy for managing pain associated with disseminated cutaneous leiomyomas.
    • Antidepressant medication may offer a viable non-surgical option for patients with extensive cutaneous leiomyoma involvement.
    • Further research is warranted to explore the efficacy and mechanisms of antidepressant treatment for leiomyoma-associated pain.