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Updated: May 22, 2026

Large-scale Top-down Proteomics Using Capillary Zone Electrophoresis Tandem Mass Spectrometry
Published on: October 24, 2018
Capillary zone electrophoresis and polymer dynamics
1Department of Physics, Worcester Polytechnic Institute, Worcester, MA 01609, USA. phillies@4liberty.net
Abstract:
Capillary electrophoresis with a polymer solution support medium is a well-established powerful analytical tool. This paper discusses a possible alternative application of capillary electrophoresis, namely a path for studying the dynamics of polymer solutions. The key to the approach is an inversion of perspective. Instead of treating the migrating species as the object of experimental importance and the support medium as being of importance only because it facilitates separations, one treats the polymer solution as being of experimental importance, and the choice of migrating species as being of interest only because different species may probe different aspects of polymer dynamics.
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