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Therapeutic options for low bone mineral density in HIV-infected subjects

Aoife G Cotter1, Patrick W G Mallon

  • 1HIV Molecular Research Group, University College Dublin, Clinical Research Centre, Nelson St., Dublin, Ireland. Aoife.cotter@ucdconnect.ie

Current HIV/AIDS Reports
|April 25, 2012
PubMed

Insights

Effective antiretroviral therapy (ART) for HIV has led to long-term complications like low bone mineral density (BMD). This review covers therapeutic options for managing low BMD in people with HIV.

Area of Science:

  • Infectious Diseases
  • Endocrinology
  • Public Health

Background:

  • Effective antiretroviral therapy (ART) has improved outcomes for HIV-infected individuals.
  • Long-term HIV infection and ART are associated with increased prevalence of low bone mineral density (BMD).
  • Managing chronic complications is crucial for HIV physicians.

Purpose of the Study:

  • To review and outline therapeutic options for low bone mineral density (BMD).
  • To provide guidance for managing low BMD specifically in HIV-infected populations.
  • To highlight the importance of addressing long-term complications of HIV and its treatment.

Main Methods:

  • Literature review of studies on bone mineral density (BMD) in HIV-infected populations.
  • Analysis of current therapeutic strategies for osteoporosis and low BMD.
  • Synthesis of evidence regarding treatments relevant to the HIV context.

Main Results:

  • Low bone mineral density (BMD) is a significant comorbidity in individuals with HIV.
  • Various therapeutic options exist for managing low BMD, some with specific considerations for HIV patients.
  • The review consolidates information on pharmacological and non-pharmacological interventions.

Conclusions:

  • Management of low bone mineral density (BMD) is an essential component of comprehensive HIV care.
  • HIV physicians should be aware of and implement appropriate therapeutic strategies for low BMD.
  • Further research may be needed to optimize BMD management in the evolving landscape of HIV treatment.

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